The second course on Practical Personalized Medicine

The second course on Practical Personalized Medicine

The second course on Practical Personalized Medicine took place the 13th April 2016 at the University of Zurich. Interested students and faculty interacted in lively discussions.

The dermatologist Alexander Navarini introduced the field of personalized medicine, the use of biomarkers for simple and complex stratification with machine learning, and the 4Ps, namely predictive, preventive, personalized and participatory medicine. Focusing on his field dermatology, he illustrated the power of stratification techniques in advanced melanoma and the use of clinical and visual data as biomarkers in inflammatory dermatoses. A medical ethics specialist gave us a historical perspective on truth in medicine and urged all participants to critically review the real advances that modern medicine achieves and not to lose sight of the 5th P, namely the patient as a person. The medical law specialist Brigitte Tag highlighted important changes in the doctor-patient relationship as a consequence of 4P medicine, as well as as yet open questions of property of genetic data, the right not to know medically relevant data, and illustrated the relevant challenges for society as a whole.
The medical geneticist Anita Rauch demonstrated fascinating case studies from her practice and showed that there is more to modern genetics than whole exome sequencing and that clinical features are crucially important for a diagnosis. The cardiologist Andreas Flammer talked about personalized risk calculations for cardiovascular events and that medium-risk patients are the hardest to evaluate with these algorithms. New, early changes like endothelial function could add value to these efforts.
The internal medicine specialist Edouard Battegay gave a fascinating talk on cluster analysis of medical data and new associations that help us understand polymorbidity.
The metabolic disease specialist Matthias Baumgartner showed new investigative approaches for extremely rare disorders such as methylmalonic acidemia ,and a mouse model that allowed him to test new, recently identified potential treatments.
The telemedicine specialist Martin Denz demonstrated the power of mobile device-derived biomarkers and that health data is collected and used ubiquitously, empowering both healthcare providers and patients.
At the end of a long day that seemed way too short, the director of research and education of the University Hospital Zurich Prof. Gabriela Senti prepared a personal certificate to all participants that Prof. Navarini distributed.